Local cochlear damage reduces local nonlinearity and decreases generator-type cochlear emissions while increasing reflector-type emissions

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Local cochlear damage reduces local nonlinearity and decreases generator-type cochlear emissions while increasing reflector-type emissions.

Distortion product otoacoustic emissions (DPOAEs) originate in cochlear nonlinearity and emerge into the ear canal as an apparent sum of emission types, one of which (generator) travels directly out and the other (reflector) travels out following linear reflection. The present study explores intracochlear sources of DPOAEs via simultaneous ear canal and intracochlear pressure measurements in ge...

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Cochlear sources and otoacoustic emissions.

Current understanding suggests that there are two different mechanisms by which otoacoustic emissions (OAEs) are generated in the cochlea. These mechanisms include a nonlinear-distortion mechanism and a coherent-reflection mechanism. Distortion product OAEs (DPOAEs) are believed to include contributions from both mechanisms, while stimulus frequency OAEs (SFOAES), at least at low and moderate l...

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Cochlear Mechanics and Otoacoustic Emissions

Local, rather than systemic, drug delivery to the inner ear is becoming more widely used to treat inner ear disorders. While many substances are undergoing preclinical and clinical studies, it is equally important to develop appropriate drug delivery systems. Pharmacokinetic studies are technically demanding in animals and almost impossible in humans. Computer simulations have helped establish ...

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Cochlear Mechanics and Otoacoustic Emissions

Background: Congenital malformations of the auricle are often combined with atresia of the outer ear canal and malformations of the ossicles, representing aesthetic as well as functional deficits. Optimal treatment should therefore address both aspects equally. This report describes a new approach, combining the reconstruction of the auricle with implantation of an active middle ear hearing aid...

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Otoacoustic emissions in time-domain solutions of nonlinear non-local cochlear models.

A nonlinear and non-local cochlear model has been efficiently solved in the time domain numerically, obtaining the evolution of the transverse displacement of the basilar membrane at each cochlear place. This information allows one to follow the forward and backward propagation of the traveling wave along the basilar membrane, and to evaluate the otoacoustic response from the time evolution of ...

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ژورنال

عنوان ژورنال: The Journal of the Acoustical Society of America

سال: 2010

ISSN: 0001-4966

DOI: 10.1121/1.3291682